The 4^th material of the journal «Science and Innovation» and the Institute of History of the National Academy of Sciences of Belarus joint project deals with the 80^th anniversary of the liberation of Belarus from the Nazi invaders, reveals in detail the preparation stages of the «Bagration» Operation.

   The Belarus’ trade secrets protecting (know-how) practice in different time periods has been summarized, and statistics on the contracts registration in the patent office in 1993–2013 provided. There have been analyzed the basic requirements to agreements on the disposal of rights to know-how. The unsolved problems in the national legislation that complicate the process of production secrets transfer have been identified.

   During the round table «Commercial value of know-how», there were discussed the legal status of know-how and it’s validation as an object of intellectual property, as well as issues of appropriate protection regime and, in general, the specificity of the institution of trade secrets.

The article deals with the economic aspects of the application of the norms on trade secrets (know-how) in connection with the constant transformation of approaches to the legal protection of this intellectual property object in the Republic of Belarus. The article considers the issues of valuation of trade secrets (know-how), reflection of operations with them in accounting, validity of their inclusion in the intangible assets of the organisation. The conclusion is made that due to the interest of the Republic of Belarus in strengthening the innovation component of the economy, it is advisable to return to the possibility of transferring the right to use the information constituting trade secrets (know-how) under the agreement rather than the information itself. This is connected with the legal definition of the object of intangible assets as a set of property rights. The authors propose to use a systematic approach to changing the rules on the acceptance of property rights to intellectual property objects for accounting as intangible assets, which can be facilitated by the choice of one of the proposed models.

   The article analyzed the protecting methods of such objects of intellectual property, as inventions, utility models, production prototypes and others used by organizations of the Republic of Belarus.

The concept of «economic potential» is widely used in national economic security research. But usually, it may turn inadequate in case of analysis trade war and politically motivated economic sanctions. We argue that it can be replaced with game theory concept of bargaining power. In the result of the change in paradigm, all the involved parties can get the common strategy of resolving the conflict. As an example, the PRC – USA trade war is taken.

The article considers the theory of formation of digital marketing strategies, points out the directions of innovative development in marketing. It also shows the circumstances that may hinder the development of digital marketing in the activities of companies. Separately, the implementation of the analytical, practical and control stage for the effective management of a digital marketing strategy is considered. t is noted that a digital marketing strategy may be part of the company’s policy. The planning of complex measures necessary to manage strategies taking into account the internal environment of the organization and adaptation to the external conditions of unstable markets is considered. A formula is presented for determining the economic performance of digital marketing projects.

   The article provides a retrospective analysis of Chinese B2B-enterprises’ distribution channels digital development.

   It is the final part of the article by Belarusian mathematicians, that allows you to understand the main thing about life and mathematics, i. e., why the simplest thing is the most complex, and also whether it is possible to take over the world with the help of one equation.

   This review focuses on primordial black holes, i.e. the black holes that were formed in the very early Universe in the prestellar era, before the formation of stars. The author presented the data on observations of antimatter in our galaxy, which was predicted within the framework.

   A set of folk customs is analyzed on the basis of many years’ field research, which symbolically combine the main miracle worker of the Christian tradition honoring and greeting of living nature before the new cycle of agricultural work.

The paper describes the functionalities of the electronic handbook of risks of agricultural production above the food safety standards that establish the maximum permissible levels of ¹³⁷Cs and ⁹⁰Sr. The handbook is based on the methods that allow to assess and analyze the risk of food non-compliance either for each radionuclide individually (137Cs or 90Sr), or simultaneously for both radionuclides (¹³⁷Cs and ⁹⁰Sr). The RISKAgro can be used as an aid tool to rapidly assess the suitability of land resources of agricultural organizations for the production of regulatory clean products in terms of existing national or harmonized Union State standards of the Republic of Belarus and the Russian Federation, as well as any new or changing legal requirements for the quality and safety of foodstuffs, feedstuffs and raw materials. Introduction of the RISKAgro handbook into agricultural practices in the areas of radioactive contamination will help to minimize contamination levels of ¹³⁷Cs and ⁹⁰Sr, improve the radiological quality of foods and prevent against production of highly contaminated agricultural produces above the established norms.

The biological marker of parthanatosis is Poly (ADP-ribose) polymerase (PARP), the activation of which is associated with various pathological processes in the body. Tumor tissue samples from patients with morphologically verified liver and colon cancer were studied. The control consisted of liver and intestinal tissues of the same patients not affected by a tumor, and intravital biopsies (native tissue) of the liver and intestines of non-cancer patients. Determination of the concentration of antibodies to PARP and determination of DNA/RNA viruses (VEB, HBV, HCV, HPV, CMV, HSV1/2, HHV6) in tissue samples was carried out by enzyme immunoassay and polymerase chain reaction method. The research results showed that the concentration of antibodies to PARP in tissue extracts from tumor processes is higher than in native tissue samples (p<0.05) and in tissue with «no criteria for malignancy» (p<0,05). The relationship between the frequency of isolation of DNA-containing viruses (HHV6, CMV, VEB) from tumor tissues and the concentration of PARP antibodies (p<0,05) suggests that DNA damage to cells is stimulated by viruses during oncogenesis of the liver and colon.