Characteristics of the immunity system in patients with pneumonia associated with COVID‑19
https://doi.org/10.29235/1818-9857-2022-2-24-35
Abstract
The advanced analysis of immune parameters describing differentiation profile, activation and exhaustion of lymphocytes, monocytes and granulocytes of patients with moderate and severe/critical COVID‑19 pneumonia was performed.
About the Authors
D. BobrukevichBelarus
Daria Bobrukevich
N. Antonevich
Belarus
Natalya Antonevich
A. Hancharou
Belarus
Andrei Hancharou
E. Rynda
Belarus
Elena Rynda
O. Timokhina
Belarus
Oksana Timokhina
Ya. Minich
Belarus
Yana Minich
E. Golovach
Belarus
Elena Golovach
M. Dotsenko
Belarus
Marina Dotsenko
E. Dotsenko
Belarus
Eduard Dotsenko
References
1. Sustained cellular immune dysregulation in individuals recovering from SARS CoV 2 infection / Files J. K. [et al.] // The Journal of Clinical Investigation. 2020. №1. P. 131
2. Coronavirus infections and immune responses / Li G. [et al.] // Journal of medical virology. 2020. V. 92. №4. P. 424–432.
3. The clinical course and its correlated immune status in COVID 19 pneumonia / Ruyuan He. [et al.] // Journal of Clinical Virology. 2020. №7. P. 127.
4. De Virgiliis, F. Lung innervation in the eye of a cytokine storm: neuroimmune interactions and COVID 19 / De Virgiliis F., Di Giovanni S. // Nature Reviews Neurology. 2020. №11, Vol. 16. P. 1–8.
5. Characteristics of peripheral lymphocyte subset alteration in COVID 19 pneumonia / Wang F. [et al.] // The Journal of infectious diseases. 2020. V. 221. №11. P. 1762–1769.
6. Phenotype of SARS CoV 2 specific T cells in COVID 19 patients with acute respiratory distress syndrome / Weiskopf D. [et al.] // Sci Immunol. 2020. V. 5. №48. eabd2071
7. Detection of SARS CoV 2 specific humoral and cellular immunity in COVID 19 convalescent individuals / Ling Ni. [et al.] // Immunity. 2020. V. 52. №6. P. 971–977.
8. Suppressed T cell mediated immunity in patients with COVID 19: a clinical retrospective study in Wuhan, China / Bo Xu. [et al.] // The Journal of infection. 2020. V. 81. №1. P. 51–60.
9. SARS CoV 2 reactive T cells in healthy donors and patients with COVID 19 / Braun J. [et al.] // Nature. 2020. №578. P. 270–274.
10. In depth phenotyping of human peripheral blood mononuclear cells in convalescent COVID 19 patients following a mild versus severe disease course / Chang Feng Chu. [et al.] // medRxiv. 2020.
11. Shared Antigen specific CD8+ T cell Responses Against the SARS COV 2 Spike Protein in HLA A* 02: 01 COVID 19 Participants / Chour W. [et al.] // medRxiv. 2020.
12. SARS CoV 2, the virus that causes COVID 19: cytometry and the new challenge for global health / Cossarizza A. [et al.] // Cytometry. 2020. V. 97. №4. P. 340–343.
13. Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID 19) / Diao B. [et al.] // Frontiers in Immunology. 2020. №11. P. 827.
Review
For citations:
Bobrukevich D., Antonevich N., Hancharou A., Rynda E., Timokhina O., Minich Ya., Golovach E., Dotsenko M., Dotsenko E. Characteristics of the immunity system in patients with pneumonia associated with COVID‑19. Science and Innovations. 2022;(2):24-35. (In Russ.) https://doi.org/10.29235/1818-9857-2022-2-24-35