<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">innosfera</journal-id><journal-title-group><journal-title xml:lang="ru">Наука и инновации</journal-title><trans-title-group xml:lang="en"><trans-title>Science and Innovations</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1818-9857</issn><issn pub-type="epub">2412-9372</issn><publisher><publisher-name>Издательский дом «Белорусская наука»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.29235/1818-9857-2025-01-74-77</article-id><article-id custom-type="elpub" pub-id-type="custom">innosfera-745</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ДИССЕРТАЦИОННЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DISSERTATION RESEARCH</subject></subj-group></article-categories><title-group><article-title>Изменение архитектоники мембраны эритроцитов у пациентов с COVID-19 и после него</article-title><trans-title-group xml:lang="en"><trans-title>Changes in the architecture of the erythrocyte membrane in patients with COVID-19 and after it</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шафорост</surname><given-names>А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shaforost</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александр Шафорост, старший научный сотрудник научно-исследовательской лаборатории </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Воропаев</surname><given-names>Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Voropaev</surname><given-names>E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евгений Воропаев, проректор по научной работе, кандидат медицинских наук, доцент</p></bio><email xlink:type="simple">voropaev.evgenii@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Гомельский государственный медицинский университет</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>18</day><month>02</month><year>2025</year></pub-date><volume>1</volume><issue>1</issue><fpage>74</fpage><lpage>77</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Издательский дом «Белорусская наука», 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Издательский дом «Белорусская наука»</copyright-holder><copyright-holder xml:lang="en">Издательский дом «Белорусская наука»</copyright-holder><license xlink:href="https://innosfera.belnauka.by/jour/about/submissions#copyrightNotice" xlink:type="simple"><license-p>https://innosfera.belnauka.by/jour/about/submissions#copyrightNotice</license-p></license></permissions><self-uri xlink:href="https://innosfera.belnauka.by/jour/article/view/745">https://innosfera.belnauka.by/jour/article/view/745</self-uri><abstract><p>Проанализировано изменение механических свойств мембраны эритроцитов у пациентов с протекающей или перенесенной инфекцией COVID-19. Выявленные различия в показателях могут быть использованы для оценки тяжести заболевания.</p></abstract><trans-abstract xml:lang="en"><p>The change in the mechanical properties of the red blood cell membrane was analyzed in patients with ongoing or past COVID-19 infection compared to the control during the observation period from 2021 to 2023. Significant differences in the friction force (p&lt;0.001) and roughness (p&lt;0.0032) of the red blood cell membrane were found in patients with acute/past coronavirus infection compared to the control. It was noted that the maximum changes in the properties of the red blood cell membrane are observed during the period of the highest incidence of COVID-19. The friction force (Fl) and roughness (Rq) of the red blood cell membrane can be used to assess the severity of past coronavirus infection, and in the future, other diseases.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эритроциты</kwd><kwd>COVID-19</kwd><kwd>атомно-силовая микроскопия</kwd><kwd>механические свойства</kwd><kwd>сила трения</kwd><kwd>шероховатость</kwd><kwd>архитектоника</kwd></kwd-group><kwd-group xml:lang="en"><kwd>red blood cells</kwd><kwd>COVID-19</kwd><kwd>atomic force microscopy</kwd><kwd>mechanical properties</kwd><kwd>friction force</kwd><kwd>roughness</kwd><kwd>architectonics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">WHO European health information at your fingertips // https://gateway.euro.who.int/en/indicators/hfa_290-1960-sdr-acute-respiratory-infections-pneumonia-andinfluenza-under-5-years-per-100-000/.</mixed-citation><mixed-citation xml:lang="en">WHO European health information at your fingertips // https://gateway.euro.who.int/en/indicators/hfa_290-1960-sdr-acute-respiratory-infections-pneumonia-andinfluenza-under-5-years-per-100-000/.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Dysregulation in erythrocyte dynamics caused by SARS-CoV-2 infection: possible role in shuffling the homeostatic puzzle during COVID-19 / M.M. Mendonça [et al.] // Rev Bras Hematol Hemoter. 2022. Vol. 44, №2. P. 235–245.</mixed-citation><mixed-citation xml:lang="en">Dysregulation in erythrocyte dynamics caused by SARS-CoV-2 infection: possible role in shuffling the homeostatic puzzle during COVID-19 / M.M. Mendonça [et al.] // Rev Bras Hematol Hemoter. 2022. Vol. 44, №2. P. 235–245.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Гематология // Б.В. Афанасьев [и др.]. – СПб., 2019.</mixed-citation><mixed-citation xml:lang="en">Гематология // Б.В. Афанасьев [и др.]. – СПб., 2019.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Шейко Л.М. Практикум по медицинской и биологической физике. Раздел «Биологическая физика»: Методы биофизических исследований // Л.М. Шейко, С.Б. Бокуть. – Минск, 2011.</mixed-citation><mixed-citation xml:lang="en">Шейко Л.М. Практикум по медицинской и биологической физике. Раздел «Биологическая физика»: Методы биофизических исследований // Л.М. Шейко, С.Б. Бокуть. – Минск, 2011.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Erythrocytes morphology and hemorheology in severe bacterial infection / A.F. Silva [et al.] // Mem Inst Oswaldo Cruz. 2019. Vol. 114. P. e190326.</mixed-citation><mixed-citation xml:lang="en">Erythrocytes morphology and hemorheology in severe bacterial infection / A.F. Silva [et al.] // Mem Inst Oswaldo Cruz. 2019. Vol. 114. P. e190326.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">АСМ-диагностика патологии эритроцитов на основе физико-механического образа клеточной поверхности / М.Н. Стародубцева [и др.] // Проблемы здоровья и экологии. 2015. №2 (44). С. 99–104.</mixed-citation><mixed-citation xml:lang="en">АСМ-диагностика патологии эритроцитов на основе физико-механического образа клеточной поверхности / М.Н. Стародубцева [и др.] // Проблемы здоровья и экологии. 2015. №2 (44). С. 99–104.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Макарова Е.С. Изучение взаимодействия вируса гриппа с единичными клетками эпителия и эритроцитами / Е.С. Макарова, И.В. Яминский // Медицина и высокие технологии. 2016. №1. С. 39–55.</mixed-citation><mixed-citation xml:lang="en">Макарова Е.С. Изучение взаимодействия вируса гриппа с единичными клетками эпителия и эритроцитами / Е.С. Макарова, И.В. Яминский // Медицина и высокие технологии. 2016. №1. С. 39–55.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Cavezzi A. COVID-19: hemoglobin, iron, and hypoxia beyond inflammation. A narrative review / A. Cavezzi, E. Troiani, S. Corrao // Clin Pract. 2020. Vol. 10, №2. P. 1271.</mixed-citation><mixed-citation xml:lang="en">Cavezzi A. COVID-19: hemoglobin, iron, and hypoxia beyond inflammation. A narrative review / A. Cavezzi, E. Troiani, S. Corrao // Clin Pract. 2020. Vol. 10, №2. P. 1271.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Filterability of Erythrocytes in Patients with COVID-19 / D.S. Prudinnik [et al.] // Biomolecules. 2022. Vol. 12, №6. P. 782.</mixed-citation><mixed-citation xml:lang="en">Filterability of Erythrocytes in Patients with COVID-19 / D.S. Prudinnik [et al.] // Biomolecules. 2022. Vol. 12, №6. P. 782.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Are mushroom-shaped erythrocytes an indicator of COVID-19? / D. Gérard [et al.] // British Journal of Haematology. 2021. Vol. 192, №2. P. 230–230.</mixed-citation><mixed-citation xml:lang="en">Are mushroom-shaped erythrocytes an indicator of COVID-19? / D. Gérard [et al.] // British Journal of Haematology. 2021. Vol. 192, №2. P. 230–230.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Soma P. Pathophysiological changes in erythrocytes contributing to complications of inflammation and coagulation in COVID-19 / P. Soma, J. Bester // Front Physiol. 2022. Vol. 13. P. 899629.</mixed-citation><mixed-citation xml:lang="en">Soma P. Pathophysiological changes in erythrocytes contributing to complications of inflammation and coagulation in COVID-19 / P. Soma, J. Bester // Front Physiol. 2022. Vol. 13. P. 899629.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Eryptosis in health and disease: A paradigm shift towards understanding the (patho) physiological implications of programmed cell death of erythrocytes / S.M. Qadri [и др.] // Blood Rev. 2017. Vol. 31, №6. С. 349–361.</mixed-citation><mixed-citation xml:lang="en">Eryptosis in health and disease: A paradigm shift towards understanding the (patho) physiological implications of programmed cell death of erythrocytes / S.M. Qadri [и др.] // Blood Rev. 2017. Vol. 31, №6. С. 349–361.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Применение атомно-силового микроскопа в медико-биологических исследованиях: Приложение к руководству пользователя атомно-силового микроскопа NT-206 / М.Н. Стародубцева [и др.]. – Гомель, 2013.</mixed-citation><mixed-citation xml:lang="en">Применение атомно-силового микроскопа в медико-биологических исследованиях: Приложение к руководству пользователя атомно-силового микроскопа NT-206 / М.Н. Стародубцева [и др.]. – Гомель, 2013.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
